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Image Search Results
Journal: Cell Death & Disease
Article Title: 𝒟(−)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent
doi: 10.1038/cddis.2012.97
Figure Lengend Snippet: Susceptibility to apoptosis of U937Bcl-2 and U937pMEP cells. Both transfectants were treated with 𝒟(−)lentiginosine at the concentration of 10, 50, 100, 250, 500 and 1000 μ M for 18 h. The data on Y-axis are expressed as percentage hypodiploid nuclei, as detected by propidium iodide staining and flow cytometry analysis. As a positive control, etoposide at the concentration of 50 μ M was used. Data are presented as mean values±S.D. from three experiments performed in duplicate ( n =6). Asterisks (**) indicate highly significant differences between treated and untreated cells ( P <0.001)
Article Snippet: Apoptosis was assessed through flow cytometry analysis of isolated nuclei stained with
Techniques: Concentration Assay, Staining, Flow Cytometry, Positive Control